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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23372 | SMIFH2 | Others | |
SMIFH2 is formin homology 2 (FH2) domains inhibitor. | |||
T4S0969 | Obtusifolin | Antioxidant , NF-κB | |
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be... | |||
T5994 | KPT-6566 | Others | |
KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity. | |||
T4102 | Goserelin acetate | Fertilan,ICI-118630 acetate,Zoladex | Apoptosis , GNRH Receptor |
Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. | |||
T7982 | 3,6-Dihydroxyflavone | Others | |
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway. | |||
T3330 | Trans-Trimethoxyresveratrol | trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene | Reactive Oxygen Species |
trans-Trimethoxyresveratrol (MR-3), a natural methoxylated analog of resveratrol, inhibits breast Y cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchy... | |||
T77701 | FL118 | FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin | Survivin |
FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin s... | |||
T38752 | EW-7195 | ALK , TGF-beta/Smad | |
EW-7195 is a selective and potent inhibitor of ALK5 (TGFβR1) with an IC50 value of 4.83 nM.EW-7195 has an affinity for ALK5 that is more than 300-fold higher than that of p38α.EW-7195 has an inhibitory effect on TGF-β1-i... | |||
T36696 | DMBA | ||
7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T36860 | C22 Sphingomyelin (d18:1/22:0) | C22 Sphingomyelin (d18:1/22:0) | |
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel... | |||
T63827 | HSP90-IN-10 | ||
HSP90-IN-10 is a potent inhibitor of HSP90. HSP90-IN-10 exhibits potent anti-proliferative effects on HCC1954 breast cancer cells (IC50: 6 μM). hSP90-IN-10 induces apoptosis without inhibiting the growth of normal epithe... | |||
T37564 | C4 Ceramide (d18:1/4:0) | C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0) | |
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used... | |||
T36497 | CAY10735 | CAY10735 | |
CAY10735 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 μM). CAY10735 inhibits migration of and the epithelial-to-mese... | |||
T36460 | CAY10736 | CAY10736 | |
CAY10736 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal ... | |||
T73419 | JMX0293 | ||
JMX0293, an O-alkylamino-tethered salicylamide derivative, demonstrates strong efficacy against the TNBC MDA-MB-231 cell line with an IC50 of 3.38 μM, while showing minimal toxicity towards the non-tumorigenic human brea... | |||
T83765 | Dendrogenin A | DDA | |
Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest... |